Toxic epidermal necrolysis and development of liver abscesses
Domínguez-Borgúa, A.és.; González, I.; Morales, L.; Martínez-Carrillo, F.M.; Palacios, P.
Gaceta Medica de Mexico 151(4): 512-518
2015
ISSN/ISBN: 0016-3813 PMID: 26290028 Document Number: 682425
Pharmacologic hypersensitivities commonly express cutaneous manifestations, and the highest mortality is found in Stevens Johnson's syndrome and toxic epidermal necrolysis, mostly associated with antibiotics and anticonvulsive drugs. Toxic epidermal necrolysis is related in 80% of cases to pharmacologic hypersensitivity and systemic consequences may be found; hepatic injury has been described, but the finding of liver abscesses has not been reported among common injuries. The case of a patient with a rapid development of multiple liver abscesses in the clinical setting of hypersensitivity due to lamotrigine and the discussion of probable etiologies and management is presented.