IVIG for the treatment of toxic epidermal necrolysis
Mittmann, N.; Chan, B.C.; Knowles, S.; Shear, N.H.
Skin Therapy Letter 12(1): 7-9
2007
ISSN/ISBN: 1201-5989 PMID: 17361314 Document Number: 611153
Intravenous immunoglobulin (IVIG) has been proposed as a treatment for toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS). A number of retrospective and prospective studies have been conducted, with varying levels of evidence for the efficacy of IVIG. Recent publications provide opposing conclusions. A multi-center, comparative, long-term analysis needs to be conducted to determine the role of IVIG in the management of patients with SJS/TEN.