Application of zebra fishes in studies on traditional Chinese medicines
Tian, L.-l.; Zhu, G.-f.
Zhongguo Zhong Yao Za Zhi 40(5): 822-827
2015
ISSN/ISBN: 1001-5302 PMID: 26087540 Document Number: 680586
The zebra fish model, as an integral animal model, features small volume, high throughput, low cost, short cycle and reliable experimental results, thus has been widely used in medical studies. Traditional Chinese medicines (TCM) constitute a complex system, their active ingredients and action mechanisms are among study hotspots in during the development of modern TCMs. Along with the constant improvement of advanced technologies and methods, zebra fishes have been increasingly applied in studies on TCMs and shown advantages in active screening, and toxicity and metabolism studies. In this paper, TCM studies by using zebra fishes in recent years are summarized to provide new ideas and methods for basic studies on TCMs.