Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus
Shibnev, V.A.; Garaev, T.M.; Finogenova, M.P.; Kalnina, L.B.; Nosik, D.N.
Voprosy Virusologii 60(2): 35-38
2015
ISSN/ISBN: 0507-4088 PMID: 26182655 Document Number: 679175
Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4. The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy.
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