Exploration for the multi-effect of cardamom in's resistance to multiple myeloma
Zhihua, Z.; Jianping, Y.; Miaomiao, S.; Kuisheng, C.
Pakistan Journal of Pharmaceutical Sciences 27(6 Suppl): 2001-2006
2014
ISSN/ISBN: 1011-601X PMID: 25410063 Document Number: 676949
This paper aimed to probe the cardamom in effect on the viability, proliferation, apoptosis and periodic function of the multiple myeloma, and explore its mechanism. We used CCK-8 method to evaluate the effect of cardamom in on the viability of PBMNCs (Persom Blood Mononuclear Normal Cells). EdU can test the influence of small cell proliferation. We used the method of PI single-staining flow cytometry, in order to test the influence of tumor cell cycle. AO (Acridine Orange), EB (Ethidium Bromide) double staining fluorescene microscope was applied to observe the influence of tumor apoptotic morphology. It can be concluded that cardamom in can inhibit the viability and proliferation of MM (Multiple Myeloma) cells and cardamom in is the anti-myeloma drug with strong viability.