Safety and survival benefit of surgical management for elderly gastric cancer patients
Bi, Y.-M.; Chen, X.-Z.; Jing, C.-K.; Zhou, R.-B.; Gao, Y.-F.; Yang, L.-B.; Chen, X.-L.; Yang, K.; Zhang, B.; Chen, Z.-X.; Chen, J.-P.; Zhou, Z.-G.; Hu, J.-K.
Hepato-Gastroenterology 61(134): 1801-1805
2014
ISSN/ISBN: 0172-6390 PMID: 25436382 Document Number: 676579
To study the safety and survival outcome of surgical management for elderly gastric cancer patients. Methods: Patients proven of gastric cancer who aged ≥80 years during November 2002 to July 2011 were retrospectively analyzed. The detailed information of patients' characteristics and surgical management was retrieved. Follow-up of overall survival status was performed to analyze the surgical effectiveness. Totally, 92 (48 in surgery and 44 in non-surgery group) out of 187 eligible patients recorded adequate information and analyzed finally. There were 34 patients undergone radical gastrectomy, 6 palliative gastrectomy, 1 gastrojejunostomy and 7 exploratory laparotomy. Median follow-up durations were 25 (9-111) and 28 (8-114) months in surgery and non-surgery groups, respectively (p=0.797). Clinical-pathological T stage and node status were comparable. Clinical-pathological distal metastasis status was 15 and 26 M1 cases for surgery and nonsurgery, respectively (p=0.006). Incidence of postoperative complications and hospital mortality were 25.0% and 2.1%, respectively. The 2-year survival rates of M0 subgroups were 35.7% and 0% for surgery and nonesurgery, respectively (HR=3.98, p=0.022). The safety of surgery for well-selected ≥ 80-year elderly gastric cancer patients was potentially acceptable and the patients of early or locally advanced diseases could obtain survival benefits by surgery.