Effect of adenosine on the shape, aggregates morphology and aggregability of ATP-depleted erythrocytes
Sheremet'ev, I.A.; Popovicheva, A.N.; Rogozin, M.M.; Levin, G.I.
Biofizika 59(3): 488-491
2014
ISSN/ISBN: 0006-3029 PMID: 25715590 Document Number: 674575
The effect of adenosine on the shape, aggregate morphology and aggregability of ATP-depleted erythrocytes was studied. It is shown that the ATP-depletion of erythrocyte leads to the change in their shape: diskocytes transform to echinocytes. It is found that the aggregability of such cells in autoplasma significantly decreased. Incubation of echinocytes with adenosine largely restored discoid shape and erythrocyte aggregability.