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Clinical immunological diagnostics of overlap syndrome during autoimmune hepatic disorders

Sagynbaeva, V.É; Lazebnik, L.B.; Gudkova, R.B.; Efremov, L.I.; Vinnitskaia, E.V.; Dorofeev, A.S.

Eksperimental'naia i Klinicheskaia Gastroenterologiia 8: 60-65

2014

ISSN/ISBN: 1682-8658
PMID: 25911914
Document Number: 673660
The complex determination of serum autoantibodies to hepatic antigens using enzyme immunoassay and immunoblot allows to increase the frequency of overlap syndrome identification during autoimmune hepatic disorders and its early diagnostics, that has a big clinical, diagnostic and prognostic importance. The levels of overlap autoantibodies combine with biochemical index and with disease activity and intensity of autoimmune processes during overlap syndrome of primary biliary cirrhosis/autoimmune hepatitis (PBC/AIH).

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