Vaccination is not always sufficient to prevent vertical transmission of hepatitis B virus
Buster, E.H.J.C.; de Man, R.A.
Nederlands Tijdschrift Voor Geneeskunde 158: A8151
2014
ISSN/ISBN: 0028-2162 PMID: 25322358 Document Number: 672583
Routine screening of pregnant women for infection with hepatitis B virus and active-passive immunization of newborns resulted in a dramatic decline in vertical transmission of hepatitis B. A recent study in the Annals of Internal Medicine identified factors associated with failure of active-passive immunization of newborns from hepatitis B virus infected mothers. A further decline in the incidence of vertical transmission of hepatitis B virus may be expected when referral for and initiation of antiviral therapy in the last trimester of pregnancy for selected patients can be optimized.
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