HLA-G 14bp del/ins genetic variation: association with susceptibility to human immunodeficiency virus-1 vertical transmission but not with human immunodeficiency virus-1 infection through horizontal transmission
Segat, L.; Crovella, S.
Tissue Antigens 80(1): 12-13
2012
ISSN/ISBN: 0001-2815 PMID: 22512775 DOI: 10.1111/j.1399-0039.2012.01874.xDocument Number: 352065
We discuss herein the possible involvement of human leukocyte antigen (HLA)-G 14bp del/ins polymorphism in human immunodeficiency virus (HIV) infection. Based on previous results and reports, we suggest that HLA-G should be considered, in the context of HIV-1 infection, as a candidate molecule for the susceptibility to HIV-1 mother-to-child transmission, rather than for HIV-1 horizontal transmission for which no consensus findings and hypothesis have been reported so far.
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