The pregnancy outcome in patients WITH β-thalassemia minor
Yordanova, D.; Nikolov, A.; Museva, A.; Karamiseva, V.
Akusherstvo i Ginekologiia 53(Suppl 1): 20-24
2014
ISSN/ISBN: 0324-0959 PMID: 25510037 Document Number: 671974
Thalassemia syndromes are heterogenic group hereditary hemoglobinopathies, provoking chronic hemolytic anemia. They affect approximately 100 million people, mostly in the Mediterranean (including Bulgaria), South-eastern Asia and Africa. Thalassemia syndromes are the second reason for hypochromic anemia and anemia in pregnancy after iron deficiency. To determine pregnancy outcome of women with β-thalassemia minor. It is an ambispective study in University Hospital of Obstetrics and Gynecology" Maichin dom", Sofia, for a year. Patients are divided in two groups regarding the presence of β-thalassemia minor. Preeclampsia, gestational diabetes mellitus, olygo- and polyhydramnion, preterm labor intrauterine growth retardation (IUGR), Cesarean section delivery are recorded in study groups. Cases with β-thalassemia minor have significantly higher prevalence of oligohydramnion and Cesarean section delivery. There is no significant difference regarding Apgar score in 1st and 5th minute, IUGR, gestational diabetes mellitus and preeclampsia between two study groups. β-Thalassemia minor does not significantly influence the pregnancy in negative way.