Reentrant cannulation of duodenum cranial to pancreatic duct in the pig
Holmes, J.H.; Horney, F.D.; Leadbeater, P.A.
American Journal of Veterinary Research 34(10): 1365-1366
1973
ISSN/ISBN: 0002-9645 PMID: 4518298 Document Number: 67185
In studies on digestive enzymes in pigs, sampled of duodenal contents cranial to the pancreatic duct were required. In one animal the duodenum was cut just below the entrance of the bile duct, 2.5 cm from the pyloric sphincter, and bypass cannulae were inserted at this point and also distal to the pancreatic duct. This method was unsatisfactory as bouts of vomiting occurred, either because of bile flow back to the stomach, or a muscular reaction to closure of the intestine near the pyloric sphincter. Another technique involved cutting the duodenum midway between the bile and pancreatic ducts. One cannula was inserted there and the other distal to the pancreatic ducts. Total collections of duodenal contents were made eight times over 12-hour periods, small amounts being retained for analaysis and the rest being passed back under slight pressure through the second cannula. The animals were killed after 1-2 months as sudden total anorexia developed and did not respond to treatment.