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Chemical constituents from twigs and leaves of Melodinus hemsleyanus

Zhang, J.; Yang, T.-T.; Li, G.-Q.; Wang, W.-J.; Zhang, X.-Q.; Ye, W.-C.

Zhongguo Zhong Yao Za Zhi 38(10): 1548-1551

2013

ISSN/ISBN: 1001-5302
PMID: 23947135
Document Number: 669493
To study the chemical constituents in the twigs and leaves of Melodinus hemsleyanus. The chemical constituents were isolated by silica gel, ODS and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. Fourteen compounds were isolated from the 95% ethanol extract of the twigs and leaves of M. hemsleyanus. Their structures were identified as 11-hydroxytabersonine (1), venalstonid (2), sandine (3), oleanolic acid (4), ursolic acid (5), betulin (6), (+)-pinoresinol (7), (-)-syringaresinol (8), 8-hydroxypinoresinol (9), (-)-latifolin (10), cirsilineol (11), loganin (12), dibutylterephthalate (13), and beta-sitosterol (14). Compounds 4-14 were obtained from this plant for the first time.

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