Cardiorespiratory responses of healthy person to increased normobaric inhalation hypoxia
Divert, É V.; Krivoshchekov, S.G.
Fiziologiia Cheloveka 39(4): 82-92
2013
ISSN/ISBN: 0131-1646 PMID: 25486834 Document Number: 667204
On almost healthy young men the changes of cardiorespiratory indexes are explored at prolonged (25 mines) exponenticaly dropping concentration of O2 in an inhalation respiratory admixture from 20.9% to 10%. It is shown that the most prompt (during 2-5 mines) is ventilatory equivalent of O2 that testifies to slope of efficacy of interlinking of oxygen in lungs grows. Individual expression of this depression is rather variable (on 22-84% from a reference value) also is substantially caused by the current alveolar ventilation spotting the basic reserve of enriching ventiljatorno-perfuzionnyh of relations in lungs. The subsequent propagation reaction of the cardiac contraction rate meeting in 100% of surveys, is impeded concerning the beginning of a hypoxia and combined with increase of the anoxemia noted on depression of a saturation of haemoglobin of blood O2. The individual gain of the cardiac contraction rate on a hypoxia compounds 8-43% from a datum level and is significantly bound to current diastolic arterial pressure of a blood. Hypoxycal ventilatory response is expressed only in 71% of cases, from which in 15%--is reversed at concomitant depression of a respiration rate.