Hepatorenal syndrome: diagnosis, treatment and prevention
Egerod Israelsen, M.; Gluud, L.Lotte.; Bendtsen, F.; Møller, Søren.; Krag, A.Ahm.
Ugeskrift for Laeger 175(22): 1562-1566
2013
ISSN/ISBN: 0041-5782 PMID: 23721840 Document Number: 666184
Cirrhosis, ascites and renal impairment are associated with high morbidity and mortality. The hepatorenal syndrome (HRS) is a type of renal failure that affects patients with cirrhosis and ascites. This paper provides an update on evidence-based interventions in HRS. A number of factors can precipitate HRS. The monitoring, prevention, early detection, and correct treatment of these are essential. Terlipressin combined with albumin is the first-line treatment of type 1 HRS. In type 2 HRS with refractory ascites, liver transplantation and TIPS should be considered.