A case of neuroendocrine cell carcinoma of the esophagus with lung metastases successfully treated with CPT-11/CDDP
Takeoka, T.; Hirao, M.; Fujitani, K.; Yamamoto, K.; Asaoka, T.; Ikenaga, M.; Miyamoto, A.; Ikeda, M.; Nakamori, S.; Sekimoto, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(12): 2121-2123
2013
ISSN/ISBN: 0385-0684 PMID: 24394033 Document Number: 664781
A 70-year-old man presented with dysphagia to another institution and was referred to our hospital. We diagnosed the patient with primary neuroendocrine cell carcinoma and squamous cell carcinoma of the esophagus. Following 2 courses of CDDP+5-FU+ADM combination neoadjuvant chemotherapy, the primary tumor had reduced in size. Thereafter, we performed subtotal esophagectomy by right thoracotomy, retrosternal gastric tube reconstruction, and 2-field lymph node dissection. Computed tomography scan 3 months after the surgery revealed lung metastasis. He received CPT-11+CDDP chemotherapy, and the disease was diagnosed as cCR. At present, he is alive without any evidence of recurrence 12 months after the surgery.