The role of insulin resistace in preeclampsia
Mladenova, M.; Dimitrakova, E.; Pehlivanov, B.; Milinova, M.; Parahuleva, N.; Bakardzhiev, I.
Akusherstvo i Ginekologiia 52(4): 5-9
2013
ISSN/ISBN: 0324-0959 PMID: 24283070 Document Number: 664262
Contemporary data show that there is a link between insulin resistance and preeclampsia (PE) due to many common features. We examined 90 pregnant women at the clinic of Obstetrics and Gynecology at the University Hospital "St.George". 35 of them were preeclamptic and 55 normotensive. Glucose levels were measured at 0, 1, 2 h after OGTT (after 75 g. oral glucose administration). Insulin levels were also measured and HOMA IR was evaluated. Fasting glucose and insulin levels were similar in both groups and showed no statistical significance. HOMA IR was higher in the preeclamptic group 2.89 vs 2.09 for normotensive group no statistical significance was shown. Our results indicate that PE is not associated with insulin resistance.