Development of ultrasound-based monitor of relative blood volume
Jiang, S.; Hu, X.; Liang, Z.; Fan, J.; Xia, W.; Zhou, H.; Yi, W.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 30(6): 1204-1208
2013
ISSN/ISBN: 1001-5515 PMID: 24645597 Document Number: 664240
Assessing dry weight accurately is crucial in providing effective and safe haemodialysis. Biases towards dry weight assessment may bring a series of dialysis complications. This study introduces an online detection technique of relative blood volume (RBV) based on ultrasound, which analyzes the correlation between changes in blood density and sound speed. By measuring the attenuation in sound velocity, this method was employed to calculate RBV, and then to evaluate the dry weight of patients on dialysis. TDC-GP2 time measurement chip and MSP430 Single-chip Microcontroller (SCM) were used in the system to measure the ultrasonic travel time. In the clinical trials, RBV values range between 71.3% and 108.1%, showing consistent result with Fresenius 4008S blood volume monitor (BVM). This detection method possesses several advantages, such as real time, convenient, reproducible, non-invasive, and etc.