Phase analysis of the cardiac cycle in patients with arterial hypertension based on the results of equilibrium radioventriculography
Matveev, V.V.; Gaĭdamakina, N.E.; Bubenov, A.S.; Podzolkov, V.I.
Klinicheskaia Meditsina 91(8): 32-36
2013
ISSN/ISBN: 0023-2149 PMID: 24437182 Document Number: 664196
To study cardiac cycle parameters in patients with grade I and II AH by equilibrium radioventriculography (ERVG) and the possibility of using them for diagnostics of systolic and diastolic myocardial dysfunction. Left and right ventricular diastolic and systolic functions were evaluated by conventional ERVG using a MB-9100 gamma-chamber (Gamma, Hungary) and the Gold-Rada+ system for data collection and processing. The study involved 142 patients divided into 3 groups. Group 1 included 38 patient with grade 1 AH (mean age 20.7 +/- 6.2 yr), group 2 85 patients with grade II AH (58.7 +/- 10.7 yr), group 3 19 practically healthy subjects (29.4 +/- 10.8 yr). No significant abnormalities in hemodynamic characteristics except increased filling of the right ventricle for 1/3 diastole were observed in group 1. Decreased filling for 1/3 diastole, maximum filling rate, and the ratio of filling to ejection rates were revealed in group 2. In order to counterbalance HR differences, the time-related ERVG values were calculated per RR interval; it allowed to reveal diastolic disorders confirmed in the study of ERVG "hemodynamics characteristics. Patients with grade II AH showed a longer time of maximum filling rate with respect to left and right ventricular RR intervals compared with controls. In group 1, this parameter was lower than in healthy subjects.