Dependence of a functionally-metabolic state of phagocytes and a complement activity from the immune deficiency degree in the patients with HIV-infection
Zhyvytsia, D.H.
Klinichna Khirurhiia 2013(5): 55-57
2013
ISSN/ISBN: 0023-2130 PMID: 23888811 Document Number: 664104
Some indices of nonspeciphic immunity were analyzed in 60 HIV-infected patients with various content of CD4-lymphocytes. In a HIV-infected persons, not depending on the CD4-lymphocytes content, the raising of the circulating immune complexes level was revealed. When the CD4-lymphocytes content is less than 200 cells in 1 microl the complement (CH50) activity is raising, bactericidal activity of phagocytes (in accordance with the HCT-test data) is lowering. These changes cause no effective intracellular elimination, enhancement of persistence of causative agents in phagocytes and their further dissemination in organism of the patients.