The analysis of detection rate of ambiguity of loci under HLA-typing by SSO technology

Loginova, M.A.; Trofimova, N.P.; Paramonov, I.V.

Klinicheskaia Laboratornaia Diagnostika 4: 29-32

2012


ISSN/ISBN: 0869-2084
PMID: 22768714
Document Number: 663574
The article deals with the results of HLA-typing of 1829 patients on loci HLA-A, HLA-B, HLA-DRB1 using kits of LABType SSO reagents (One Lambada, USA). The indicators of each locus ambiguity are determined: locus HLA-A - 4.43%, locus HLA-B--4.43%, locus HLA-DRB1--0.16%. The list of "rare" alleles was applied to analyze 13 types of determined ambiguities on locus HLA-A, 27 types on locus HLA-B, 3 types on locus HLA-DRB1.

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