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Disseminated kidney tuberculosis complicating autosomal dominant polycystic kidney disease: a case report

Takeshita, H.; Amemiya, M.; Chiba, K.; Urushibara, M.; Satoh, J-Ichi.; Noro, A.

Clinical Nephrology 77(3): 242-245

2012

ISSN/ISBN: 0301-0430
PMID: 22377257
Document Number: 662817
Mycobacterium tuberculosis infection in patients with autosomal dominant polycystic kidney disease (ADPKD) is rare, and its diagnosis and treatment are difficult because numerous cysts are exposed to infection and antibiotics do not easily penetrate infected cysts. Here, we report the case of a 43-year-old Japanese man with disseminated urogenital tuberculosis (TB) and ADPKD without human immunodeficiency virus (HIV) infection. Delayed diagnosis and ineffective anti-TB chemotherapy worsened his condition. Finally, he underwent bilateral nephrectomy but experienced postoperative complications. In conclusion, kidney TB should be recognized as a cause of renal infection in ADPKD, and surgical treatment should be instituted without delay. The importance of early diagnosis and treatment cannot be overemphasized to prevent kidney TB deterioration.

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