Primary cold agglutinin disease: a case report
Das, S.Kumar.; Ghosh, A.; Banerjee, N.; Khaskil, S.; Mukherjee, S.Sachi.
Journal of the Indian Medical Association 110(10): 741-742
2012
ISSN/ISBN: 0019-5847 PMID: 23738411 Document Number: 662416
Chronic cold agglutinin disease is a subgroup of auto-immune haemolytic anaemia. Primary cold agglutinin disease has traditionally been defined by the absence of any underlying or associated disease. It usually affects elderly. The term cold refers to the fact that the auto-antibody involved reacts with red cells poorly or not at all at 37 degrees C, whereas it reacts strongly at lower temperature. Here a case of severe pallor, jaundice and red colour urine in winter season for last 10 years diagnosed as a case of primary cold agglutinin disease is reported.The patient was managed conservatively.