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Cholera vibrios lectins as main pathogenicity and persistence factors (biotechnological aspects of use)

Telesmanich, N.R.; Lomov, I.M.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2: 93-99

2012

ISSN/ISBN: 0372-9311
PMID: 22693819
Document Number: 661510
Literature data and results of our studies of lectins are analyzed in the review. All the leading pathogenicity factors of cholera vibrios that possess enzymatic activity--cholera toxin, hemolysin, neuraminidase, chitinase have several lectin domains, that determine not only their pathogenetic role but also open perspectives for their use in medical practice. At the same time the variable receptor profile of cholera vibrios cells of various biovars and epidemical significance established with hemagglutination inhibition reaction by carbohydrates could be used to develop new principles of testing and typing of cholera vibrios.

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