Preservation of cholerogenicity in cholera vibrios in the incomplete L-cycle stage
Emdina, I.A.; Podosinnikova, L.S.; Somova, A.G.; Miliutin, V.N.; Prozorovskiĭ, S.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 11: 82-86
1979
ISSN/ISBN: 0372-9311 PMID: 390934 Document Number: 152252
The work presents the characteristics of the forms appearing as a result of the incomplete L cycle of Vibrio cholerae obtained in experimental conditions after the cultivation of typical V. eltor strain, serovar Ogawa, for 5 months at room temperature in sterile river water without subculturing. The culture formed shaprly changed L-similar colonies, had decreased agglutinability and was resistant to diagnostic cholera phages, but retained its cholerogenicity for suckling rabbits. A suggestion was made concerning the possible epidemiological significance of such forms and the necessity of their detection in the course of bacteriological analysis for cholera.