Case of metastatic malignant melanoma detected by multifocal cerebral hemorrhage
Shinomiya, A.; Okada, M.; Hatakeyama, T.; Shindo, A.; Nakamura, T.; Kawanishi, M.; Miyake, K.; Kawai, N.; Tamiya, T.
No Shinkei Geka. Neurological Surgery 40(3): 261-269
2012
ISSN/ISBN: 0301-2603 PMID: 22392756 Document Number: 660615
We encountered a case of intracranial metastatic malignant melanoma which caused repeated multiple hemorrhage. Intracranial metastatic malignant melanoma showed high intensity in the magnetic resonance imaging's T1 weighted image, low intensity in T2 weighted image and very low intensity in T2* weighted image. Positron emission tomographic scans are useful for systemic evaluation of active malignancies. The present case underwent tumor removal following re-bleeding. The patient died of repeated hemorrhage one month after the operation. Intracranial metastatic malignant melanoma has a strong propensity to cause intracerebral hemorrhage leading to clinical deterioration. We think that the development of a therapeutic strategy for the treatment of intracranial metastatic malignant melanoma, including its risk management of intracerebral hemorrhage would be great importance.