Study on the weight-reducing effect of Acer truncatum leave extract in alimentary obesity rat
Gao, L.; Cao, L.; Tian, M.; Chen, Z.
Wei Sheng Yan Jiu 41(4): 609
2012
ISSN/ISBN: 1000-8020 PMID: 23057325 Document Number: 659940
To investigate the weight-reducing effect of Acer truncatum leave extract on alimentary obesity rats and its effect on fatty acid synthase (FAS). SPF-grade adult male Wistar rats were fed with high-fat diet and Acer truncatum leave extract (10, 30 and 100 mg/kg BW) was given by gavage once a day for 31 days. Body weight (BW), adipose weight and food consumption were recorded, and the activity of hepatic fatty acid synthase (FAS) was measured. Compared with the model-control group, body weight, adipose weight and the ratio of adipose weight to body weight were obviously lower in 30 mg/kg BW and 100 mg/kg BW groups (P < 0.01). The activity of hepatic FAS in rats administrated with the extract was markedly lower than the control rats (P < 0.05). There might have a function of Acer truncatum leave extract on reducing body weight.