Systemic chemotherapy and chemoradiotherapy for advanced pancreatic cancer
Ueno, H.; Okusaka, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 39(3): 357-363
2012
ISSN/ISBN: 0385-0684 PMID: 22421761 Document Number: 657855
Currently, we are able to use S-1 with gemcitabine and erlotinib, as well as gemcitabine alone, as first-line therapy for advanced pancreatic cancer. In addition, a clinical trial of FOLFIRINOX is underway in Japan. On the other hand, chemoradiotherapy is considered to be one of the treatments of choice for locally advanced pancreatic cancer. This review summarizes current knowledge about non-surgical treatment for advanced pancreatic cancer, mainly based on the results of recent clinical trials.
Document emailed within 1 workday
Related Documents
Gansauge, F.; Ramadani, M.; Schwarz, M.; Beger, H.G.; Lotspeich, E.; Poch, B. 2007: The clinical efficacy of adjuvant systemic chemotherapy with gemcitabine and NSC-631570 in advanced pancreatic cancer Hepato-Gastroenterology 54(75): 917-920Watanabe, F.; Honda, G.; Kurata, M.; Tsuruta, K.; Tokashiki, T.; Funada, N. 2009: A case report-neoadjuvant chemoradiotherapy with combination of S-1 and gemcitabine in a patient with locally advanced pancreatic cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 36(12): 2430-2432
Jelavić, T.Boraska.; Miše, B.Petrić.; Strikic, A.; Ban, M.; Vrdoljak, E. 2015: Adjuvant Chemotherapy in Locally Advanced Cervical Cancer After Treatment with Concomitant Chemoradiotherapy--Room for Improvement? Anticancer Research 35(7): 4161-4165
Seddik, Y.; Brahmi, S.Aziz.; Afqir, S. 2019: Does Adjuvant Chemotherapy for Locally Advanced Resectable Rectal Cancer treated with Neoadjuvant Chemoradiotherapy have an impact on survival? A Single Moroccan Institute Retrospective Study Gulf Journal of Oncology 1(30): 29-32
Berlin, J.D.; Rothenberg, M. 2001: Chemotherapy for resectable and advanced pancreatic cancer Oncology 15(10): 1241-1249; 1254; Discussion: 1254-1264
Ozaki, H.; Ishii, K. 1972: Systemic chemotherapy of pancreatic cancer Gan no Rinsho. Japan Journal of Cancer Clinics 1972(Suppl): 382-384
Hayashi, K.; Uchida, K.; Hatori, T.; Takasaki, K. 2006: TS-1: S-1 based chemotherapy for far-advanced or relapsed pancreatic cancer Nihon Rinsho. Japanese Journal of Clinical Medicine 64(Suppl 1): 194-197
Choi, M.; Razzaque, S.; Kim, R. 2012: Systemic therapy of advanced pancreatic cancer: has the landscape changed? Clinical Advances in Hematology and Oncology: H&o 10(7): 442-451
Ohkawa, S. 2006: Gemcitabine chemotherapy for patients with advanced or relapsed pancreatic cancer Nihon Rinsho. Japanese Journal of Clinical Medicine 64(Suppl 1): 198-202
Lee, H-W.; Choi, J-H.; Lim, H-Y.; Park, J.S.; Kim, H.C.; Kang, S.; Oh, Y.T.; Chun, M.; Sheen, S.S.; Oh, Y.J.; Park, K.J.; Hwang, S.C. 2006: The addition of induction chemotherapy with etoposide, ifosfamide, and cisplatin failed to improve therapeutic outcome of concurrent chemoradiotherapy in patients with locally advanced non-small cell lung cancer -- single institution retrospective analysis Neoplasma 53(1): 30-36
Taoka, H.; Hirano, H.; Mitsui, Y.; Umino, W.; Nobuoka, Y.; Yamashita, M.; Tanigawa, K.; Yoshimine, S.; Imai, T.; Kadowaki, S.; Miyashita, K.; Ikuma, H.; Nakamura, T.; Murata, T. 2004: Adjuvant chemotherapy for unresectable locally advanced pancreatic cancer in light of its characteristics Gan to Kagaku Ryoho. Cancer and ChemoTherapy 31(9): 1365-1370
Matsumoto, G.; Tsuruta, K.; Okamoto, A.; Karasawa, K.; Kamata, N. 2006: Chemoradiotherapy including intraoperative radiotherapy for advanced and relapsed pancreatic tumors Nihon Rinsho. Japanese Journal of Clinical Medicine 64(Suppl 1): 243-247
Liu, X.; Chen, J.; Yao, W. 1999: Arterial infusion chemotherapy combined with concurrent radiotherapy for local advanced pancreatic cancer Zhonghua Zhong Liu Za Zhi 21(5): 369-370
Scher, H.I. 1992: Systemic chemotherapy in regionally advanced bladder cancer. Theoretical considerations and results Urologic Clinics of North America 19(4): 747-759
Iwasaki, Y.; Ohashi, M.; Nunobe, S.; Iwanaga, T.; Iwagami, S.; Takahashi, K.; Yamaguchi, T.; Matsumoto, H.; Nakano, D. 2008: Treatment for advanced gastric cancer with positive lavage cytology-systemic versus intraperitoneal chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 35(12): 2009-2011
Fujimoto, C.; Maruyama, Y.; Niina, Y.; Fujimori, N.; Sumii, T.; Funakoshi, A. 2008: A case of advanced pancreatic cancer responding to combination chemotherapy with the individual maximum repeatable dose of gemcitabine and oral S-1 Gan to Kagaku Ryoho. Cancer and ChemoTherapy 35(6): 1013-1016
Ishiguro, A.; Munakata, M.; Shitara, K.; Suzuki, K.; Takahata, T.; Itoh, J.; Sakata, Y.; Munakata, A. 2007: A case of unresectable advanced gallbladder cancer treated by systemic chemotherapy combined with hepatic arterial infusion Gan to Kagaku Ryoho. Cancer and ChemoTherapy 34(7): 1127-1130
Nishiofuku, H.; Tanaka, T.; Anai, H.; Sueyoshi, S.; Yamamoto, K.; Morimoto, K.; Maeda, S.; Masada, T.; Sho, M.; Nakajima, Y.; Tamamoto, T.; Hasegawa, M.; Sakaguchi, H.; Kichikawa, K. 2010: Locally advanced pancreatic cancer successfully treated by arterial infusion chemotherapy combined with stereotactic radiotherapy--a case report Gan to Kagaku Ryoho. Cancer and ChemoTherapy 37(12): 2315-2318
Wada, T.; Kunisaki, C.; Hasegawa, S.; Kaida, S.; Tamura, S.; Ono, H.; Oshima, T.; Fujii, S.; Kosaka, T.; Makino, H.; Akiyama, H.; Endo, I. 2013: A case of locally advanced gastric cancer in which the patient underwent curative gastrectomy after treatment with systemic chemotherapy with bi-weekly s-1/docetaxel Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(11): 1533-1536
Deng, X.; Jin, X.; Xue, S.; Zhang, X.; Su, H.; Zhang, P.; Xie, C. 2014: Postoperative chemoradiotherapy for advanced gastric cancer after D2 gastrectomy Hepato-Gastroenterology 61(133): 1472-1477