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Stereotactic proton irradiation of cerebral arteriovenous malformations in patients with onset of disease in childhood

Gerasimov, S.V.; Vinogradov, V.M.; Garmashov, I.A.; Shalek, R.A.

Voprosy Onkologii 57(2): 236-240

2011

ISSN/ISBN: 0507-3758
PMID: 21809672
Document Number: 655278
The report discusses the results of proton stereotactic irradiation in 27 children, aged 6-15 (mean--12.5 yrs.), and 21 adults, aged 16-47 (mean--23 yrs.), with arteriovenous malformations (AVM) in the brain. The AVM volume ranged 0.2-37.7 cu cm; absorbed dosage at dose field maximum--40-80 Gy. Complete AVM obliteration was attained in 17 (35%) (mean AVM volume--3.1 cu cm); 50% decrease and more--12 (25%)(mean AVM volume--7 cu cm). When AVM volume was cut down to less than 50% (9) (19%) (mean AVM volume--9.2 cu cm) and 10 (21%) (mean AVM volume--19.6 cu cm), no effect was reported.

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