Metabotropic glutamate receptors as targets for new drug development
Arkhipov, V.I.; Kapralova, M.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 74(10): 46-52
2011
ISSN/ISBN: 0869-2092 PMID: 22238988 Document Number: 654404
The review is devoted to experimental investigations of metabotropic glutamate receptors and the properties of drugs (ligands) belonging to agonists, antagonists, and modulators of the activity of these receptors. Possibilities of the treatment of neurodegenerative disorders, cognitive disturbances in schizophrenia patients, and narcotic dependency by using drugs of this class are considered.
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