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Anti-inflammatory and immune modulation therapy against atherosclerosis

Yamashita, T.; Hirata, K.-I.

Nihon Rinsho. Japanese Journal of Clinical Medicine 69(1): 168-172

2011

ISSN/ISBN: 0047-1852
PMID: 21226279
Document Number: 652680
Atherosclerosis is a chronic inflammatory disease and many kinds of inflammatory cells and their releasing molecules are profoundly associated with the initiation and progression of the disease. However, we never have clinical therapeutic methods to directly intervene the inflammation or to modulate the immune system for preventing atherosclerosis so far. This article will focus on the recent experimental anti-inflammatory and immune modulatory therapies including active vaccination and induction of immune tolerance. We introduce our new experimental trial to develop a new immune therapy against atherosclerosis. We hope some novel therapies could be applied to clinics in the near future.

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