Top Abstract Purchase Related
Home
>
Node
>
Subnode

Antiviral humanized and human monoclonal antibodies

Lashkevich, V.A.

Voprosy Virusologii 56(5): 4-8

2011

ISSN/ISBN: 0507-4088
PMID: 22171470
Document Number: 652642
The paper considers the characteristics of monoclonal antibodies, methods for their experimental preparation, problems of their production, and possibilities of their use for the emergency prevention of viral infections and for the treatment of chronic diseases caused by human immunodeficiency virus, hepatitis B and C viruses, and herpes viruses. The future of experimentally produced or clinically trialed monoclonal antibodies is mainly determined by commercial considerations. It is possible that simplification of industrial production technologies and a reduction in the cost of evidence-based methods for evaluation of clinical effectiveness will allow monoclonal antibodies to be extensively used for the prevention and treatment of viral infections.

Document emailed within 1 workday
Secure & encrypted payments

Sawada, T.; Hashimoto, S. 2007: Human monoclonal antibody to B-lymphocyte stimulator (belimumab) and humanized anti-LFA-1 monoclonal antibodies (efalizumab) Nihon Rinsho. Japanese Journal of Clinical Medicine 65(7): 1239-1242
Caron, P.C.; Co, M.S.; Bull, M.K.; Avdalovic, N.M.; Queen, C.; Scheinberg, D.A. 1992: Biological and immunological features of humanized M195 (anti-CD33) monoclonal antibodies Cancer Research 52(24): 6761-6767
Delmonico, F.L.; Knowles, R.W.; Colvin, R.B.; Cavender, D.E.; Kawai, T.; Bedle, M.; Stroka, D.; Preffer, F.I.; Haug, C.; Cosimi, A.B. 1993: Immunosuppression of cynomolgus renal allograft recipients with humanized OKT4A monoclonal antibodies Transplantation Proceedings 25(1 Part 1): 784-785
Furukawa, K.; Yamaguchi, H.; Oettgen, H.F.; Old, L.J.; Lloyd, K.O. 1989: Two human monoclonal antibodies reacting with the major gangliosides of human melanomas and comparison with corresponding mouse monoclonal antibodies Cancer Research 49(1): 191-196
Onuma, E.; Sato, K.; Saito, H.; Tsunenari, T.; Ishii, K.; Esaki, K.; Yabuta, N.; Wakahara, Y.; Yamada-Okabe, H.; Ogata, E. 2004: Generation of a humanized monoclonal antibody against human parathyroid hormone-related protein and its efficacy against humoral hypercalcemia of malignancy Anticancer Research 24(5a): 2665-2673
Ramakrishnan, S.; Houston, L.L. 1984: Comparison of the selective cytotoxic effects of immunotoxins containing ricin a chain or pokeweed antiviral protein and anti-Thy 1.1 monoclonal antibodies Cancer Research 44(1): 201-208
Hughes, E.J.; Eichbaum, Q.; Beatty, D.W. 1991: Human monoclonal antibodies: analysis of two antibodies derived from lymphocytes of a patient with acute rheumatic fever Medical Laboratory Sciences 48(4): 244-255
James, K. 1990: Human monoclonal antibodies and engineered antibodies in the management of cancer Seminars in Cancer Biology 1(3): 243-253
Agius, M.A.; Geannopoulos, C.J.; Fairclough, R.H.; Richman, D.P. 1988: Monoclonal anti-idiotopic antibodies against myasthenia-inducing anti-acetylcholine receptor monoclonal antibodies. Preponderance of nonparatope-directed antibodies affecting antigen binding Journal of Immunology 140(1): 62-68
Chernokhvostova, E.V.; Kotova, T.S.; Atovmian, O.I.; Arsen'eva, E.L.; Bogacheva, G.T.; Rokhlin, O.V. 1989: Immunoenzyme test system with monoclonal antibodies to human IgG4 in the determination of allergen-specific antibodies in pollinosis Biulleten' Eksperimental'noi Biologii i Meditsiny 108(11): 574-577
Uchigata, Y.; Prabhakar, B.S.; Salata, K.F.; Ginsberg-Fellner, F.; Notkins, A.L. 1987: Human monoclonal multiple-organ-reactive autoantibodies distinguished by mouse monoclonal anti-idiotypic antibodies: expression of idiotopes in humans with and without autoimmune diseases Journal of Immunology 138(12): 4218-4221
Deriugina, E.I.; Olovnikova, N.I.; Lemeneva, L.N.; Belkina, E.V.; Udalov, G.A.; Chertkov, I.L. 1991: Monoclonal antibodies to Rho(D)-antigen of the Rhesus system. Obtaining the EBV-transformed B-lymphoblastoid human cell lines secreting IgG-anti-D antibodies Gematologiia i Transfuziologiia 36(8): 11-16
Wagener, C.; Yang, Y.H.; Crawford, F.G.; Shively, J.E. 1983: Monoclonal antibodies for carcinoembryonic antigen and related antigens as a model system: a systematic approach for the determination of epitope specificities of monoclonal antibodies Journal of Immunology 130(5): 2308-2315
Woodhouse, C.S.; Morgan, A.C. 1989: Murine monoclonal IgG3 antibodies to human colorectal tumor-associated antigens: production and characterization of antibodies active in both antibody-dependent cellular cytotoxicity and complement-mediated cytolysis Cancer Research 49(10): 2766-2772
Someya, A.; Kondo, H. 1986: Human monoclonal anti-nuclear antibodies produced by human-mouse heterohybridomas Clinical and Experimental Immunology 63(1): 26-31
Hutas, G. 2008: Ocrelizumab, a humanized monoclonal antibody against CD20 for inflammatory disorders and B-cell malignancies Current Opinion in Investigational Drugs 9(11): 1206-1215
Ditzel, H.; Erb, K.; Borup-Christensen, P.; Nielsen, B.; Jensenius, J.C. 1991: Evaluation of procedures for the fixation and processing of human tissue for immunohistochemical analysis of human monoclonal antibodies Human Antibodies and Hybridomas 2(3): 135-141
Chida, J. 1984: Monoclonal antibodies produced by human-human hybridomas Gan to Kagaku Ryoho. Cancer and ChemoTherapy 11(1): 157-164
Kan-Mitchell, J.; Mitchell, M.S. 1989: Human monoclonal antibodies Progress in Clinical and Biological Research 288: 85-94
Co, M.S.; Avdalovic, N.M.; Caron, P.C.; Avdalovic, M.V.; Scheinberg, D.A.; Queen, C. 1992: Chimeric and humanized antibodies with specificity for the CD33 antigen Journal of Immunology 148(4): 1149-1154