An unusual case of hepatic carcinosarcoma
Lai, Q.; Levi Sandri, G.B.; Melandro, F.; Di Laudo, M.; Garofalo, M.; Guglielmo, N.; Grieco, M.; Di Tondo, U.; Rossi, M.; Berloco, P.B.
Il Giornale di Chirurgia 32(8-9): 372-373
2011
ISSN/ISBN: 0391-9005 PMID: 22018259 Document Number: 652540
We report a rare case of a hepatic carcinosarcoma with rabdomyosarcomatous differentiation in its sarcomatous component. A 71-year old Caucasian female patient underwent a liver resection for a 4-cm lesion developed on an underlying HCV-related cirrhosis. Post-operative course was uneventful and the patient was discharged 5 days after surgery. At pathology, the tumor presented the features of hepatocellular carcinoma and rhabdomyosarcoma Three months later the patient experienced a liver recurrence, dying 2 months later for systemic disease. The reported case presents several peculiarities, i.e. the female gender, the HCV-related cirrhotic status, and the European origin of the patient. However, the outcome of our case confirms that this neoplasm pursues a highly aggressive course with poor prognosis.