Papova virus in urine after renal transplantation
Lecatsas, G.; Prozesky, O.W.; van Wyk, J.; Els, H.J.
Nature 241(5388): 343-344
1973
ISSN/ISBN: 0028-0836 PMID: 4573127 Document Number: 65220
The excretion of viruses of the papova type in urine following renal transplantation has been described only in a single case1. Excretion of herpes viruses is more common, and a high incidence of warts in transplant patients has also been reported2. A papova-like virus has been found in brain material of patients with progressive multifocal leuco-encephalopathy (PML) and such viruses have been cultured from cases of Pml complicating Hodgkin's disease3,4. Immuno-suppressive therapy activates latent viruses5 and is associated with a high incidence of malignant tumours6. We report here the excretion in urine of a papova-like virus by approximately 45% of patients in a renal transplant unit.