Recurrence of erythema induratum of Bazin in a patient under chemotherapy for breast cancer
Vena, G.A.; Apruzzi, D.; Vestita, M.; Panaro, M.; Carpagnano, S.; Filannino, R.; Cassano, N.
New Microbiologica 34(3): 331-333
2011
ISSN/ISBN: 1121-7138 PMID: 21811756 Document Number: 652185
Erythema induratum of Bazin (EIB) is a chronic nodular eruption occurring on the lower legs of young and middleaged women which is considered the most common tuberculid. A 54-year-old woman, in treatment with chemotherapy for breast cancer, presented subcutaneous erythematous plaques and nodules on the lower limbs. She had been diagnosed with EIB 3 years earlier and diagnostic work-up showed at that time signs suggestive of latent tuberculosis. The suspect of a recurrent form of EIB was confirmed by histopathological examination. A peculiar feature of our report consists in the recurrence of EIB, which is regarded as a hyperergic response against M. tuberculosis antigens, in a patient who was receiving chemotherapy with well-known immunosuppressive effects.