Successful pregnancy following a single fresh embryo transfer in a 45-year-old woman whose early follicular phase serum follicle stimulating hormone was 29 mIU/ml
Check, J.H.; Choe, J.K.; Cohen, R.
Clinical and Experimental Obstetrics and Gynecology 38(4): 335-337
2011
ISSN/ISBN: 0390-6663 PMID: 22268269 Document Number: 651632
To determine if a successful pregnancy is possible following in vitro fertilization embryo transfer (IVF-ET) in a woman of advanced reproductive age with diminished egg reserve. In vitro fertilization-embryo transfer with intracytoplasmic sperm injection (ICSI) was performed for a 45-year-old woman with a peak serum follicle stimulating hormone (FSH) level of 29 mIU/ml and a history of failing to conceive in five previous IVF-ET cycles at a younger age. A minimal FSH stimulation protocol was used. A fresh transfer of a 7-cell embryo was performed on day 3. A successful pregnancy and delivery ensued. This case report establishes a precedent that a successful pregnancy following IVF-ET is possible in a woman whose serum FSH is > 15 mIU/ml, and is age 45. Of course, there is no implication that accomplishing this again in another woman with similar circumstances would be likely.