PTEN, tau-AP-3, thymidylate synthase immunohistochemistry scoring expression in patients with uterine leiomyomas, uterine smooth muscle tumors of uncertain malignancy potential and uterine leiomyosarcomas
Huang, L.C.; Ye, J.C.; Hsieh, C.H.; Chen, L.M.; Lin, T.Y.; Hung, Y.C.; Chang, W.C.
European Journal of Gynaecological Oncology 32(5): 496-499
2011
ISSN/ISBN: 0392-2936 PMID: 22053660 Document Number: 651349
Uterine smooth muscle tumors are frequently classified as benign and malignant. However, an assortment of mitotic counts and nuclear atypia can be indecisive between uncertain malignant potential, and malignant uterine smooth muscle tumors. We applied three immunohistochemical parameters to distinguish between cases of benign, malignant, and those with uncertain malignant histology.