Serum immunoboichemical markers in patients suffered with hypertension-induced cerebrovascular diseases
Elistratova, E.I.; Gruden', M.A.; Davydova, T.V.; Sherstnev, V.V.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 3: 25-28
2011
ISSN/ISBN: 0031-2991 PMID: 22279736 Document Number: 649978
Complex evaluation neurotrophic protein S100b, differentiation factor HLDF, idio-and antiidiotypic antibodies against these proteins in patient sera with hypertension-induced cerebrovascular disorders was performed by ELISA. In patients with essential hypertension, cerebral hypertensive crisis and ischemic stroke S100b and anti-S100b concentration was found to be higher, whereas HLDF and anti-HLDF ones were lower compared with control. Different dynamics of S100b, HLDF content and antibody level was shown within 21 days of observation. These findings may be useful in further diagnostic and prognostic studies of hypertension-induced cerebrovascular disorders.