The clinical research of contrast-enhanced sonography in evaluating renal cortical perfusion during follow up of PTRAS
Zhang, L.; Liang, W.; Xue, G.-h.; Ye, M.; Fang, H.; Zhang, J.-w.
Zhonghua Yi Xue Za Zhi 90(11): 752-755
2010
ISSN/ISBN: 0376-2491 PMID: 20627020 Document Number: 647575
To investigate the feasibility of contrast-enhanced sonography in the evaluating renal cortical perfusion. Thirteen patients with renal artery stenosis (RAS) >or= 50% were included. Technos Du8 and CnTI technology were used in the pre and post treatment of percutaneous transluminal renal artery angioplasty with stent (PTRAS). Differences in area under curve (AUC) were used to quantitate renal cortex perfusion change during follow up of PTRAS. Contrast-enhanced sonography showed significantly reduced peak flow rate by improving the renal trunk artery patency with PTRAS. AUC ratio was (6.41 +/- 38.14)% in PTRAS renal vs (-9.65 +/- 24.35)% in contralateral renal during 3 - 6 months follow up (P > 0.05). They had no statistical difference. Otherwise, Severe stenosis of renal artery (>or= 75%) show the decreased AUC ratio of (-5.19 +/- 45.88)% in 7 cases vs (19.95 +/- 23.61)% with midrange stenosis (50% - 75%) in 6 cases (P < 0.05). Contrast-enhanced sonography may provide a sensitive detection of change of the renal cortical microcirculation with the helpful to estimate therapeutic effect of PTRAS.