The bioavailability of zinc oxide nanoparticles. Study using methods of radionuclide indicators
Raspopov, R.V.; Buzulukov, I.P.; Marchenkov, N.S.; Solov'ev, V.Iu.; Demin, V.F.; Kalistratova, V.S.; Gmoshinskiĭ, I.V.; Khotimchenko, S.A.
Voprosy Pitaniia 79(6): 14-18
2010
ISSN/ISBN: 0042-8833 PMID: 21395099 Document Number: 646384
Zinc oxide nanoparticles labeled with 65Zn were administered once intragastrically to male Wistar rats. The distribution of radionuclide-marker (65Zn) was measured by gamma-spectrometer in tissue samples of animals the organs through 4 hours, 1, 3 and 5 days after administration, and in the wastes of animals through 1 since 5 days. The data obtained demonstrate for the first time the bioavailability of zinc trace element in the form of its oxide nanoparticles.