In vivo efficacy of Ingavirin against pandemic a (H1N1/09) v influenza virus

Shishkina, L.N.; Nebol'sin, V.E.; Skarnovich, M.O.; Kabanov, A.S.; Sergeev, A.A.; Erdyneeva, U.B.; Serova, O.A.; Demina, O.K.; Agafonov, A.P.; Stavskiĭ, E.A.; Drozdov, I.G.

Antibiotiki i Khimioterapiia 55(5-6): 32-35

2010


ISSN/ISBN: 0235-2990
PMID: 21033472
Document Number: 645877
Ingavirin was shown to be efficient in inhibition of the pandemic influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v. as well as the influenza virus strain A/Aichi/2/68 (H3N2) in the lungs of the infected mice. After oral administration of Ingavirin the titers of the influenza virus strains in the lung homogenates lowered.

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