A nested case-control study on the influencing factors of tuberculosis among people living with HIV/AIDS in Hunan province
Chen, M.-s.; Yang, H.-l.; Chen, Y.-f.; Tan, H.-z.; Bai, L.-q.; Zhang, Y.-h.; Liu, J.; Li, G.-p.
Zhonghua Liu Xing Bing Xue Za Zhi 31(2): 151-154
2010
ISSN/ISBN: 0254-6450 PMID: 21215073 Document Number: 572351
To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the co-infection. A 1:2 matched nested case-control study was carried out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS. 1018 people living with HIV/AIDS were followed up for one year with a total number of 736.75 person-years, among them 62 tuberculosis cases were diagnosed. The incidence density of tuberculosis among people living with HIV/AIDS was 8.42 persons per 100 person-years. Factors as education level(OR = 0.483), vaccination history of Bacille Calmette Guerin (OR = 0.561), CD(4)(+) count T-lymphocyte (OR = 0.356), unemployment (OR = 1.976), living alone (OR = 2.646), and smoking (OR = 2.215) were significantly related to the prevalence of tuberculosis among people living with HIV/AIDS. High education level, with vaccination history of Bacille Calmette Guerin and high level of CD(4)(+) T-lymphocyte count were protective factors while being unemployed, living alone, and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HIV/AIDS.