Laser photodynamic therapy of septic wounds
Tostykh, P.I.; Derbenev, V.A.; Kuleshov, I.I.; Azimshoev, A.M.; Tamrazova, O.B.; Romanova, A.S.; Karakhanov, T.I.; Solov'eva, A.B.
Khirurgiia 12: 17-22
2010
ISSN/ISBN: 0023-1207 PMID: 21311467 Document Number: 644554
Two comparable groups, 60 patients in each, were included in the study. Localization and area of the wounds, as well as basic treatment were equal in these groups. Patients of the main group received the additional photodynamic therapy with chlorine photosensibilizing agent. It led to the shortening of the wound clearing time and stimulation of the epithelisation together with fast decrease of bacterial load. Morphologic analysis showed faster inflammation decrease and granulation as well as lesser microcirculatory disorders in wounds treated with photodynamic therapy. Moreover, cicatrixes were more elastic and gentle in these patients.