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Congenital neoplasms

Biernat, W.

Polish Journal of Pathology Official Journal of the Polish Society of Pathologists 52(4 Suppl): 191-203

2001

ISSN/ISBN: 1233-9687
PMID: 11987607
Document Number: 6442
Jest to grupa chorób dziedzicznych, które sa uwarunkowane wrodzonymi mutacjami (gennlinemutations)okreslonych genów, które sa obecne we wszystkich komórkach somatycznych danego osobnika. Charakteryzuja sie one czestym wystepowaniem rodzinnym pewnych scisle zdefiniowanych nowotworów, którym niekiedy towarzysza inne zmiany nienowotworowe. Nowotwory OUN wystepujace rodzinnie naleza najczesciej do nastepujacych zespolów: - nerwiakowlókniakowatosc typu 1; - nerwiakowlókniakowatosc typu 2; - stwardnienie guzowate; - zespól von Hippel-Lindau; - zespól Cowdena; - zespól Li-Fraumeni; - zespól Turcot; - zespól znamieniowych raków (nabloniaków) podstawnokomórkowych (Gorlina).

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Congenital neoplasms

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