Identification of Cryptosporidium hominis in a patient with sclerosing cholangitis and AIDS
Carnevale, S.; Néstor Velásquez, J.; Marta, E.; Germán Astudillo, O.; Etchart, C.; Víctor Chertcoff, A.ín.; Di Risio, C.
Acta Gastroenterologica Latinoamericana 40(3): 271-275
2010
ISSN/ISBN: 0300-9033 PMID: 21053488 Document Number: 644151
Cryptosporidium hominis (C hominis) is the most common protozoan parasite recognized in human patients with AIDS. We report the clinical features of a patient with chronic diarrhea and AIDS-related sclerosing cholangitis. The imaging studies with ultrasonography and endoscopic retrograde cholangiopancreatography disclosed intrahepatic and extrahepatic bile duct changes identical to those seen in sclerosing cholangitis. C hominis was detected in the duodenum and peri-papillary duodenum by means of light microscopy and confirmed by nested polymerase chain reaction (PCR) amplification from fresh biopsy specimens followed by restriction length polymorphism analysis. Chominis infection should be suspected in our country in patients with advanced immunodeficiency and AIDS-related sclerosing cholangitis.