Identification of Enterocytozoon bieneusi in a patient with sclerosing cholangitis and AIDS
Velásquez, J.N.; Carnevale; Bessaso, H.; Bramajo, J.; Kuo, L.; Fainboim, H.
Acta Gastroenterologica Latinoamericana 30(1): 47-51
2000
ISSN/ISBN: 0300-9033 PMID: 10855355 Document Number: 519453
Enterocytozoon bieneusi is the most common microsporidian parasite found in patients with AIDS. We report the clinical features of a patient with chronic diarrhea, pancreatitis, and AIDS-related sclerosing cholangitis. Ultrasonography and endoscopic retrograde cholangiopancreatography disclosed intrahepatic and extrahepatic bile duct changes identical to those seen in sclerosing cholangitis. Enterocytozoon bieneusi was found in duodenum and peripapillary duodenum by means of light microscopy, and confirmed by PCR amplification of paraffin-embedded tissues with species-specific primers. Microsporidian infection should be suspected in patients with advanced immunodeficiency and AIDS-related sclerosing cholangitis in our country.