Green tea ameliorates renal oxidative damage induced by gentamicin in rats
Abdel-Raheem, I.T.; El-Sherbiny, G.A.; Taye, A.
Pakistan Journal of Pharmaceutical Sciences 23(1): 21-28
2010
ISSN/ISBN: 1011-601X PMID: 20067862 Document Number: 644109
Recent studies indicate that free radicals are important mediators of renal damage induced by gentamicin (GM), an aminoglycoside antibiotic widely used in treating severe gram-negative infections. Green tea extract (GTE) was reported to have antioxidant and free radical scavenging activities. Therefore, the aim of this work was to investigate the possible protective effect of GTE against gentamicin-induced nephrotoxicity. For this purpose, rats were divided into four groups.