Atypical carcinoid of the lung with abnormal elevation of serum ProGRP level; report of a case
Ito, T.; Kim, K.; Taira, M.; Kinoshita, M.; Ikeda, N.
Kyobu Geka. Japanese Journal of Thoracic Surgery 63(6): 505-507
2010
ISSN/ISBN: 0021-5252 PMID: 20533746 Document Number: 644066
We report a rare case of an atypical carcinoid of the lung with the elevation of serum ProGRP. A 79-year-old female was referred to our hospital presenting with an abnormal shadow by a chest X-ray film. Chest computed tomography (CT) scan revealed a well-defined solitary nodule in the left lower lobe. The serum level of ProGRP was elevated to 2.267 pg/ml (normal range: <46 pg/ml). Pulmonary carcinoid was pathologically suggested by a transbronchial lung biopsy. Considering the patient's general condition, a partial wide resection was performed. Pathological diagnosis was atypical carcinoid. After the operation, further increase of the serum ProGRP level was noted, and multiple liver metastases developed.