Clinical features of 215 stage i ovarian tumors in Japanese women
Kaku, S.; Takeshima, N.; Umayahara, K.; Furuta, R.; Akiyama, F.; Takizawa, K.
European Journal of Gynaecological Oncology 31(4): 395-398
2010
ISSN/ISBN: 0392-2936 PMID: 20882880 Document Number: 641754
Differences of the clinical features of Stage I borderline ovarian tumors and Stage I ovarian cancer need to be clarified. We retrospectively investigated 215 patients with Stage I ovarian tumors (67 with borderline tumors and 148 with ovarian cancer) treated between 1988 and 2001. Only one patient with a borderline tumor developed recurrence, while recurrence was found in 20 patients with Stage I ovarian cancer. There was a significant difference in the recurrence rate between patients with Stage Ia or Ib ovarian cancer and those with Stage Ic cancer (p = 0.007). Clear cell adenocarcinoma showed a higher recurrence rate. Among our patients with recurrence, only five in whom the recurrent tumor could be surgically resected are currently alive and disease-free. This study confirmed the low aggressiveness of Stage I borderline ovarian tumors and high aggressiveness of Stage Ic ovarian cancer or clear cell adenocarcinoma. In patients with recurrence, surgical resection may improve survival.