Generalized acanthosis nigricans related to type B insulin resistance syndrome: a case report
Jeong, K-Heon.; Oh, S-Joon.; Chon, S.; Lee, M-Hyoung.
Cutis 86(6): 299-302
2010
ISSN/ISBN: 0011-4162 PMID: 21284281 Document Number: 641691
Acanthosis nigricans (AN) is a cutaneous marker for many underlying states such as endocrine abnormality, obesity, certain drugs, and malignancy. Generalized AN is a rare condition and is commonly seen in adults with an underlying malignancy. The type B insulin resistance syndrome, a rare autoimmune disorder, is caused by the autoantibodies to the insulin receptor. Patients typically present with hyperglycemia but also may present with hypoglycemia. We report a rare case of a 36-year-old man with generalized AN and type B insulin resistance syndrome with hypoglycemia.